Research on Motor Neuron Diseases Konzo and Neurolathyrism: Trends from 1990 to 2010

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Research on Motor Neuron Diseases Konzo and Neurolathyrism: Trends from 1990 to 2010

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A clear association between seasonal outbreaks of a paralytic disease called konzo and toxic effects from consumption of insufficiently processed bitter cassava roots has been demonstrated in Bandundu region, Zaire. A community-based survey of 6764 inhabitants identified 110 live and 24 dead konzo-affected persons with a history of isolated non-progressive spastic paraparesis of abrupt onset. T...

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Although many use the term ‘motor neuron disease’ to refer to amyotrophic lateral sclerosis (ALS), the most common and serious of these disorders occurring in adults, there are a wide variety of different motor neuron diseases, of varying severity, affecting all ages from infancy onwards (Table 1). This death of motor neurons is a form of neurodegenerative disease and results in paralysis of th...

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ژورنال

عنوان ژورنال: PLoS Neglected Tropical Diseases

سال: 2012

ISSN: 1935-2735

DOI: 10.1371/journal.pntd.0001759